Found 46 matching trials
Open Label Study With Imetelstat to Determine Effect of Imetelstat in Patients w/ Previously Treated Multiple Myeloma
PHASE2This is an open label Phase II study to determine the rate of improvement i...
Location
University of Maryland Medical Center - M & S Greenebaum Cancer Center
Study of AMG 706 in Subjects With Advanced Gastrointestinal Stromal Tumors (GISTs)
PHASE2This study will determine the safety and effectiveness of AMG 706 in patien...
Location
Multiple Locations
Imetelstat as Maintenance Therapy After Initial Induction Chemotherapy in Non-small Cell Lung Cancer (NSCLC)
PHASE2The purpose of this is to evaluate the efficacy and safety of imetelstat (G...
Location
Achieve Clinical Research, Llc
Safety and Dose Study of GRN163L Administered to Treat Patients With Refractory or Relapsed Multiple Myeloma
PHASE1The purpose of this study is to determine the safety and the maximum tolera...
Location
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University
Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma
PHASE1The purpose of this study is to determine the best dose of imetelstat when ...
Location
CHU Sainte-Justine
To Evaluate the Safety, Tolerability and Pharmacokinetics of AMG 386 When Used in Combination With AMG 706, Bevacizumab, Sorafenib, or Sunitinib.
PHASE1The purpose of this study is to evaluate the safety, tolerability and pharm...
Location
Multiple Locations
Effect of Different Doses of AMG 706 on the Gallbladder in Advanced Solid Tumors
PHASE1The study involves the use of three different dosing regimens of AMG 706 in...
Location
Multiple Locations
Study of GRN163L With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Non Small Cell Lung Cancer
PHASE1The purpose of this study is to determine the safety and the maximum tolera...
Location
University of Maryland Greenebaum Cancer Center
AMG 706 in Treating Patients With Persistent or Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer
PHASE2RATIONALE: AMG 706 may stop the growth of tumor cells by blocking some of t...
Location
Providence Saint Joseph Medical Center - Burbank
Open Label Study to Evaluate the Activity of Imetelstat in Patients With Essential Thrombocythemia or Polycythemia Vera
PHASE2This is a phase II open-label study of single agent imetelstat in patients ...